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KMID : 0385320130240010050
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Journal of Korean Psychoanalytic Society
2013 Volume.24 No. 1 p.50 ~ p.57
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Effect of Short-Term Dynamic Psychotherapy on Brain Function of a Patient with Major Depressive Disorder: A Case Report
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Ku Jeong-Il
Kang Eun-Ho
Hong Tak-Yoo
Yu Bum-Hee
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Abstract
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Objectives: This study aimed to examine changes of brain function before and after short-term psychodynamic psychotherapy in a patient with major depressive disorder (MDD).
Methods: We recruited a patient with MDD, and a well-trained psychotherapist administered 26 sessions of short-term dynamic psychotherapy for the patient. Before and after psychotherapy, we assessed the patient’s psychological states using the Korean Version of Hamilton Depression Rating Scale (K-HDRS), and also measured the patient’s brain function using the [18] fluorodeoxy glucose ([18F]FDG) positron emission tomography.
Results: The score of K-HDRS decreased from 17 to 11 after the treatment. Decreased [18F]FDG uptake was found in the right precentral gyrus, right inferior parietal lobule, medial dorsal nucleus of right thalamus, right middle occipital gyrus, right lingual gyrus, and left cuneus after the treatment. Increased [18F]FDG uptake was found in the right precuneus, left superior occipital gyrus, left middle temporal gyrus, left parahippocampal gyrus, and left insula after the treatment.
Conclusion: This study showed the clinical improvement and changes in brain function in a MDD patient after short-term dynamic psychotherapy. We suggest that a well-designed comparison study may be necessary in order to explore brain areas which are involved in the improvement of depression after short-term dynamic psychotherapy.
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KEYWORD
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Short-term dynamic psychotherapy, Major depressive disorder, Positron emission tomography
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